Brazilian Journal of Pain
https://brjp.org.br/article/doi/10.5935/2595-0118.20210053
Brazilian Journal of Pain
Original Article

Chronic neuropathic pain: quality of life, depressive symptoms and distinction between genders

Dor crônica neuropática: qualidade de vida, sintomas depressivos e distinção entre os sexos

Laura Figueiredo Villa; Ana Marcia Rodrigues Cunha; Lilian Andreia Chessa Dias; Marcos Henrique Dall'aglio Foss; Marielza Regina Ismael Martins

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Abstract

BACKGROUND AND OBJECTIVES: Neuropathic pain is a chronic pain which can be accompanied by comorbidities, such as sleep interferences and anxiety. The present study aimed to evaluate the neuropathic chronic pain impact and its comorbidities in life quality and depression symptoms, comparing this impact between genders.

METHODS: Thirty female and 30 male patients were evaluated. The research was based on the following instruments: half structured interview with sociodemographic questions, World Health Organization Quality of Life-BREF questionnaire, Beck Depression Inventory, pain signs and symptoms by Leeds Assessment of Neuropathic Symptoms and Signs, visual analog scale and drugs adherence by Morisky-Green test.

RESULTS: As for quality of life, the physical domain was the most affected and only the psychological domain showed statistical differences between genders (p=0.031). The depression symptoms were observed in 56.7% of all patients, without important statistical difference between the genders (p=0,830). The median of pain intensity was 8.0 points, indicating severe pain intensity among these patients. The medical adherence happened among women and men, respectively in 7 (23.3%) and 11 (36.7%) of the patients (p=0.260).

CONCLUSION: The presence of neuropathic pain and its comorbidities strongly and negatively affects quality of life and is related to depressive symptoms, with similar prevalence in both genders, although women have a greater impact on their quality of life.

Keywords

Chronic pain, Depression, Gender distribution, Quality of life

Resumo

JUSTIFICATIVA E OBJETIVOS: A dor neuropática é uma dor crônica que pode se apresentar junto com comorbidades, como interferências no sono e ansiedade. O presente estudo teve como objetivo avaliar o impacto da dor crônica neuropática e suas comorbidades na qualidade de vida e sintomas depressivos, comparando esse impacto entre os sexos.

MÉTODOS: Foram incluídos 30 pacientes do sexo feminino e 30 do sexo masculino. Os instrumentos utilizados foram: entrevista semiestruturada com questões sociodemográficas, questionário de qualidade de vida World Health Organization Quality of Life-BREF, Inventário Beck de Depressão, sinais e sintomas da dor através do questionário Leeds Assessment of Neuropathic Symptoms and Signs, escala analógica visual e adesão farmacológica pelo teste de Morisky-Green.

RESULTADOS: Em relação a qualidade de vida, o domínio físico foi o mais acometido e apenas o domínio psicológico apresentou diferença estatística entre os sexos (p=0,031). Os sintomas depressivos foram observados em 56,7% dos pacientes, sem diferença significante entre os sexos (p=0,830). A mediana de intensidade dolorosa foi 8,0 pontos, indicando dor intensa nesses pacientes. A adesão farmacológica foi menor nas mulheres que nos homens, respectivamente, em 7 (23,3%) e 11 (36,7%) pacientes (p=0,260).

CONCLUSÃO: A presença de dor neuropática e suas comorbidades impacta negativamente a qualidade de vida e está relacionada com sintomas depressivos, com prevalência semelhante nos dois sexos, apesar de as mulheres apresentarem maior impacto na qualidade de vida.

Palavras-chave

Depressão, Distribuição por sexo, Dor crônica, Qualidade de vida

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Submitted date:
02/02/2020

Accepted date:
09/13/2021

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