Brazilian Journal of Pain
https://brjp.org.br/article/doi/10.5935/2595-0118.20210068
Brazilian Journal of Pain
Review Article

Migraine and sleep deprivation: integrative review

Migrânea e privação do sono: revisão integrativa

Tania Gouvêa Thomaz; Ana Ester Amorim de Paula; Daniel de Moraes Alves; Luana Lemos Alves; Pedro Guilherme Mol da Fonseca

http://dx.doi.org/10.5935/2595-0118.20210068 BrJP, vol.4, n4, p.379-387, 2021
PDF English
PDF Português
SciELO
Downloads: 0
Views: 506

Abstract

BACKGROUND AND OBJECTIVES: Migraine is a type of primary headache, and its pathophysiology remains incomplete. The relationship between sleep and migraine is easily identified by migraine patients. The aim of this review was to investigate the relationship between sleep deprivation and migraine.

CONTENTS: A search was made for articles using the terms: “migraine” and “sleep deprivation” in the Pubmed, Biblioteca Virtual da Saúde (Virtual Health Library - LILACS and IBECS) and Scielo databases. The first analysis was based on title and abstract. In cases where the title and abstract were not clear, the article was accessed in its entirety. After applying the exclusion criteria, 49 articles remained. These articles were analyzed and organized into two tables: one for articles that treated sleep as a trigger and the other for articles that explored the pathophysiological relationship between sleep and migraine.

CONCLUSION: It is possible that sleep deprivation causes or worsens migraine crisis due to its ability to cause oxidative stress in the brain. This in turn activates TRPA1 receptors located on first-order trigeminal neurons. Activation of these receptors initiates the sensitization process of the trigeminal system that culminates with the antidromic release of calcitonin gene-related peptide in the dural afferents of these neurons in the trigeminal ganglion. The relationship between insomnia and migraine seems to converge with this same pathophysiological process, since sleep deprivation imposed by insomnia would be able to generate a migraine crisis through increased oxidative stress.

Keywords

Headache, Migraine disorders, Sleep deprivation

Resumo

JUSTIFICATIVA E OBJETIVOS: Migrânea é um tipo de cefaleia primária e sua fisiopatologia permanece incompleta. A relação entre o sono e a migrânea é facilmente identificada pelos pacientes migranosos. O objetivo deste estudo foi investigar a relação entre privação de sono e a migrânea.

CONTEÚDO: Foi feita uma busca por artigos utilizando os termos: “migraine” e “sleep deprivation” nas bases de dados Pubmed, Biblioteca Virtual da Saúde (LILACS e IBECS) e Scielo. A primeira análise foi feita com base no título e no resumo. Nos casos em que o título e o resumo não foram esclarecedores, o artigo foi acessado na íntegra. Após a aplicação dos critérios de exclusão, restaram 49 artigos. Estes artigos foram analisados e organizados em duas tabelas: uma destinada aos artigos que tratavam o sono como um gatilho e a outra com artigos que exploravam a relação fisiopatológica entre sono e migrânea.

CONCLUSÃO: É possível que a privação do sono provoque ou agrave as crises de migrânea devido a sua capacidade de causar estresse oxidativo no cérebro, que ativa receptores TRPA1 localizados nos neurônios trigeminais de 1a ordem. A ativação destes receptores inicia o processo de sensibilização do sistema trigeminal que culmina com a liberação antidrômica de peptídeo relacionado ao gene da calcitonina nos aferentes durais destes neurônios no gânglio trigeminal. A relação da insônia com a migrânea parece confluir para este mesmo processo fisiopatológico, já que a privação de sono imposta pela insônia seria capaz de gerar a crise migranosa através do aumento do estresse oxidativo.

Palavras-chave

Cefaleia, Privação do sono, Transtornos de migrânea

References

Blau JN. Migraine: theories of pathogenesis. Lancet. 1992;339(8803):1202-7.

Blau JN. Migraine pathogenesis: the neural hypothesis reexamined. J Neurol Neurosurg Psychiatry. 1984;47(5):437-42.

Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurology. 2018;17(2):174-82.

Ashina M. Migraine. N Engl J Med. 2020;383(19):1866-76.

Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97(2):553-622.

Sahota RK, Dexter JD. Sleep and headache syndromes: a clinical review. Headache. 1990;30(2):80-4.

Rains JC. Optimizing circadian cycles and behavioral insomnia treatment in migraine. Curr Pain Headache Rep. 2008;12(3):213-9.

Tran DP, Spierings EL. Headache and insomnia: their relation reviewed. Cranio. 2013;31(3):165-70.

Stark CD, Stark RJ. Sleep and chronic daily headache. Curr Pain Headache Rep. 2015;19(1):468.

Vgontzas A, Pavlovic JM. Sleep disorders and migraine: review of literature and potential pathophysiology mechanisms. Headache. 2018;58(7):1030-9.

Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T. Migraine and sleep disorders: a systematic review. J Headache Pain. 2020;21(1):126.

Pavkovic IM, Kothare SV. Migraine and sleep in children: a bidirectional relationship. Pediatr Neurol. 2020;109:20-7.

Calhoun AH, Ford S. Behavioral sleep modification may revert transformed migraine to episodic migraine. Headache. 2007;47(8):1178-11783.

Rosenberg L, Butler N, Seng EK. Health behaviors in episodic migraine: why behavior change matters. Curr Pain Headache Rep. 2018;22(10):65.

Lovati C, D’Amico D, Raimondi E, Mariani C, Bertora P. Sleep and headache: a bidirectional relationship. Expert Review of Neurotherapeutics. 2010;10(1):105-17.

Lateef T, Swanson S, Cui L, Nelson K, Nakamura E, Merikangas K. Headaches and sleep problems among adults in the United States: Findings from the National Comorbidity Survey–Replication Study. Cephalalgia. 2010;31(6):648-53.

Rasmussen BK. Migraine and tension-type headache in a general population: precipitating factors, female hormones, sleep pattern and relation to lifestyle. Pain. 1993;53(1):65-72.

Robbins L. precipitating factors in migraine: a retrospective review of 494 patients. Headache. 1994;34(4):214-6.

Turner LC, Molgaard CA, Gardner CH, Rothrock J F, Stang PE. Migraine trigger factors in a non-clinical Mexican-American population in San Diego county: implications for etiology. Cephalalgia. 1995;15(6):523-30.

Alders EE, Hentzen A, Tan CT. A community-based prevalence: study on headache in Malaysia. Headache. 1996;36(6):379-84.

Chabriat H, Danchot J, Michel P, Joire JE, Henry P. Precipitating factors of headache a prospective study in a national control-matched survey in migraineurs and nonmigraineurs. Headache. 1999;39(5):335-8.

Bánk J, Márton S. Hungarian Migraine Epidemiology. Headache. 2000;40(2):164-9.

Spierings ELH, Ranke AH, Honkoop PC. Precipitating and aggravating factors of migraine versus tension-type headache. Headache. 2001;41(6):554-8.

Ierusalimschy R, Moreira Filho PF. Fatores desencadeantes de crises de migrânea em pacientes com migrânea sem aura. Arq Neuropsiquiatr. 2002;60(3-A):609-13.

Zivadinov R, Willheim K, Sepic-Grahovac D, Jurjevic A, Bucuk M, Brnabic-Razmilic O. Migraine and tension-type headache in Croatia: a population-based survey of precipitating factors. Cephalalgia. 2003;23(5):336-43.

Karli N, Zarifoglu M, Calisir N, Akgoz S. Comparison of pre-headache phases and trigger factors of migraine and episodic tension-type headache: do they share similar clinical pathophysiology?. Cephalalgia. 2005;25(6):444-51.

Wöber C, Holzhammer J, Zeitlhofer J, Wessely P, Bingol Ç W. Trigger factors of migraine and tension-type headache: experience and knowledge of the patients. J Headache Pain. 2006;7(4):188-95.

Kelman L. The triggers or precipitants of the acute migraine attack. Cephalalgia. 2007;27(5):394-402.

Fukui PT, Gonçalves TR, Strabelli CG, Lucchino NM, Matos FC. Trigger factors in migraine patients. Arq Neuropsiquiatr. 2008;66(3-A):494-9.

Bokhari FA, Sami W, Shakoori TA, Ali SA, Qureshi GA. Clinical characteristics of 226 college-going female migraineurs in Lahore, Pakistan - putting ICHD-2 to the road test. Neuro Endocrinol Lett. 2008;29(6):965-70.

Andress-Rothrock D, King W, Rothrock J. An analysis of migraine triggers in a clinic-based population. Headache. 2010;50(8):1366-70.

Yadav RK, Kalita J, Misra UK. A Study of triggers of migraine in India. Pain Med. 2010;11(1):44-7.

Carod-Artal FJ, Ezpeleta D, Martín-Barriga ML, Guerrero AL. Triggers, symptoms, and treatment in two populations of migraneurs in Brazil and Spain A cross-cultural study. J Neurol Sci. 2011;304(1-2):25-8.

Haque B, Rahman KM, Hoque A, Hasan AT, Chowdhury RN, Khan SU. Precipitating and relieving factors of migraine versus tension type headache. BMC Neurol. 2012;12:82.

Wang J, Huanga Q, Li N, Tana G, Chenb L, Zhou J. Triggers of migraine and tension-type headache in China: a clinic-based survey. Eur J Neurol. 2013;20(4):689-96.

Iliopoulos P, Damigos D, Kerezoudi E, Limpitaki G, Xifaras M, Skiada D. Trigger factors in primary headaches subtypes: a cross-sectional study from a tertiary center in Greece. BMC Res Notes. 2015;8:393.

Park J W, Chu MK, Kim JM, Park SG, Cho SJ. Analysis of trigger factors in episodic migraineurs using a smartphone headache diary applications. PLoS One. 2016;11(2).

Peris F, Donoghue S, Torres F, Mian A, Wober C. Towards improved migraine management: Determining potential trigger factors in individual patients. Cephalalgia. 2017;37(5):452-63.

Lisicki M, Romagnoli ER, Piedrabuena R, Giobellina R, Schoenen J, Magis D. Migraine triggers and habituation of visual evoked potentials. Cephalalgia. 2018;38(5):988-92.

Portela MC, Becerra DE, Zapata J P, Martínez JD, Rodriguez LM. Prevalencia de migraña y caracterización de una población estudiantil universitaria, Medellín, 2014. Med UPB. 2018;37(2):107-15.

Tai MS, Yet SXE, Lim TC, Pow YZ, Goh CB. Geographical differences in trigger factors of tension-type headaches and migraines. Curr Pain Headache Rep. 2019;23(2):12.

Inamorato E, Minatti-Hanntjch SN, Zukerman E. The role of sleep in migraine attacks. Arq Neuropsiquiatr. 1993;51(4):429-32.

Kelman L, Rains JC. Headache and sleep: examination of sleep patterns and complaints in a large clinical sample of migraineurs. Headache. 2005;45(7):904-10.

Gallup AC, Gallup JR GG. Yawning and thermoregulation. Physiol Behav. 2008;95(1):10-6.

Yeung WF, Chung KF, Won CY. Relationship between insomnia and headache in community-based middle-aged Hong Kong Chinese women. J Headache Pain. 2010;11(3):187-95.

Houle TT, Butschek RA, Turner DP, Smitherman TA, Rains JC. Stress and sleep duration predict headache severity in chronic headache sufferers. Pain. 2012;153(12):2432-40.

Engstrom M, Hagen K, Bjork M, Gravdahl GB, Sand T. Sleep-related and non-sleep-related migraine: interictal sleep quality, arousals and pain thresholds. J Headache Pain. 2013;14(1):68.

Engstrom M, Hagen K, Bjork MH, Stovner LJ, Gravdahl GB, Stjern M. Sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study. J Headache Pain. 2013;14(1):12.

Engstrom M, Hagen K, Bjork MH, Stovner LJ, Sand T. Sleep quality and arousal in migraine and tension-type headache: the headache-sleep study. Acta Neurol Scand. 2014;129(198):47-54.

Walters AB, Hamer JD, Smitherman TA. Sleep disturbance and affective comorbidity among episodic migraineurs. Headache. 2014;54(1):116-24.

Borkum JM. Migraine triggers and oxidative stress: a narrative review and synthesis. Headache. 2016;56(1):12-35.

Woldeamanuel YW, Cowan RP. The impact of regular lifestyle behavior in migraine: a prevalence case–referent study. J Neurol. 2016;263(4):669-76.

Kim J, Cho SJ, Kim WJ, Yang KI, Yun CH, Chu MK. Insufficient sleep is prevalent among migraineurs: a population-based study. J Headache Pain. 2017;18(1):50.

Song TJ, Yun CH, Cho SJ, Kim WJ, Yang KI, Chu MK. Short sleep duration and poor sleep quality among migraineurs: A population-based study. Cephalalgia. 2018;38(5):855-64.

Bertisch SM, Li W, Buettner C, Mostofsky E, Rueschman M, Kaplan ER. Nightly sleep duration, fragmentation, and quality and daily risk of migraine. Neurology. 2020;94(5):489-96.

Navarro-Pérez M P, Suller-Marti A, Bellosta-Diago E, Roche-Bueno JC, Santos-Lasaosa S. Impact of 24-hour on-call shifts on headache in medical residents: a cohort study. Headache. 2020;60(7):1427-31.

Sateia MJ. International classification of sleep disorders-third edition: highlights and modifications. Chest. 2014;146(5):1387-94.

Rechtschaffen A, Bergmann BM. Sleep rebounds and their implications for sleep stage substrates: a response to benington and heller. Sleep. 1999;22(8):1038-43.

Gallup AC. Yawning as a brain cooling mechanism: nasal breathing and forehead cooling diminish the incidence of contagious yawning. Evolution Psychol. 2007;5(1):92-101.

Giffin NJ, Ruggiero L, Lipton RB, Silberstein SD, Tvedskov J F, Olesen J. Premonitory symptoms in migraine an electronic diary study. Neurology. 2003;60(6):935-40.

Everson CA, Smith CB, Sokoloff L. Effects of prolonged sleep deprivation on local rates of cerebral energy metabolism in freely moving rats. J Neurosci. 1994;14(11):6769-78.

Krauchi K, Cajochen C, Justice AW. Thermophysiologic aspects of the three-process-model of sleepiness regulation. Clin Sports Med. 2005;24(2):287-300.

Krauchi K, Deboer T. The interrelationship between sleep regulation and thermoregulation. Front Biosci. 2010;15:604-25.

Preti A. Orexins (hypocretins): their role in appetite and arousal. Curr Opin Investig Drugs. 2002;3(8):1199-206.

Hoffmann J, Supronsinchai W, Akerman S, Andreou A P, Winrow CJ. Evidence for orexinergic mechanisms in migraine. Neurobiol Dis. 2015;74:137-43.

Borkum JM. The migraine attack as a homeostatic, neuroprotective response to brain oxidative stress: preliminary evidence for a theory. Headache. 2018;58(1):118-35.

Nassini R, Materazzi S, Benemei S, Geppetti P. The TRPA1 channel in inflammatory and neuropathic pain and migraine. Rev Physiol Biochem Pharmacol. 2014;167(1):1-43.

Benemei S, De Cesaris F, Fusi C, Rossi E, Lupi C, Geppetti P. TRPA1 and other TRP channels in migraine. J Headache Pain. 2013;14(1):71.

Benemei S, Fusi C, Trevisan G, Geppetti P. The TRPA1 channel in migraine mechanism and treatment. Br J Pharmacol. 2014;171(10):2552-67.

Borkum JM. Brain energy deficit as a source of oxidative stress in migraine: a molecular basis for migraine susceptibility. Neurochem Res. 2021;46(8):1913-32.

Gross EC, Lisicki M, Fischer D, Sándor PS, Schoenen J. The metabolic face of migraine - from pathophysiology to treatment. Nat Rev Neurol. 2019;15(11):627-43.

Submitted date:
08/04/2021

Accepted date:
09/21/2021

61e71adea9539557162231a2 brjp Articles
2595-3192 (Electronic) 2595-0118 (Printed)
BrJP ©2024 All rights reserved.

BrJP

Share this page
Page Sections