Brazilian Journal of Pain
Brazilian Journal of Pain
Review Article

Cannabinoids for the treatment of autism and childhood epilepsy

Canabinoides no tratamento do autismo e epilepsia infantil 

Paula Maria Preto Mimura; Lisiane Seguti Ferreira; Carla Leal Pereira

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BACKGROUND AND OBJECTIVES: Epilepsy and autism spectrum disorder (ASD) are diseases with neuropsychiatric impairment, which, depending on their clinical presentation, can be treated with medical cannabis. The objective of this work is to present a brief review of the literature on the use of cannabinoids (CNB) in the management of ASD and epilepsy. 
CONTENTS: The elaboration of this review was made from search and selection. Searches were carried out in the following databases: LILACS, Medline via Pubmed, Scielo and Cochrane Library, published from January 2010 to December 2022. 
CONCLUSION: The use of CNB, both for epilepsy and for ASD, has been shown to be safe, however actual effectiveness has yet to be proven.


Autism, Cannabidiol, Cannabis, Epilepsy.


JUSTIFICATIVA E OBJETIVOS: A epilepsia e o transtorno do espectro do autismo (TEA) são doenças com comprometimento neuropsiquiátrico, os quais, dependendo da sua apresentação clínica, podem ser tratados com a cannabis medicinal. O objetivo deste estudo foi apresentar uma breve revisão da literatura sobre o uso de canabinoides (CNB) no manejo do TEA e da epilepsia. 
CONTEÚDO: A elaboração desta revisão foi feita a partir de busca e seleção. Foram realizadas buscas nas bases de dados: LILACS, Medline via Pubmed, Scielo e Cochrane Library, publicados no período de janeiro de 2010 a dezembro de 2022. 
CONCLUSÃO: O uso dos CNB, tanto para epilepsia quanto para o TEA, tem se mostrado seguro, porém a real eficácia ainda não foi comprovada.


Autismo, Canabidiol, Cannabis, Epilepsia


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65553698a953952b7a114022 brjp Articles


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