Practical aspects of the use of medicinal cannabis in chronic pain
Aspectos práticos do uso da cannabis medicinal em dor crônica
Wellington Briques; Carla Leal Pereira; Paulo Sergio Feliz
Abstract
Keywords
Resumo
JUSTIFICATIVA E OBJETIVOS: As evidências têm revelado um papel importante sobre o uso da cannabis medicinal e da interação do sistema endocanabinoide com outros fármacos para o tratamento de dor crônica neuropática e nociplástica. O objetivo deste estudo foi prover atualização sobre os dados publicados quanto a doses e cuidados com o uso dos canabinoides que mostrem interação na fisiopatologia da dor crônica e seu tratamento.
CONTEÚDO: Foi realizada uma revisão baseada em pesquisa na base de dados Medline, Pubmed com uso dos unitermos “cannabis e dor”, “endocannabinoid”, “neuropathic pain”, “nociplastic pain” e “drug interactions”.
CONCLUSÃO: A interação farmacológica com os canabinoides requer aprofundamento do conhecimento científico e as doses são individuais, o que dificulta a criação de um protocolo para tratamento.
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Referências
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Submetido em:
08/09/2022
Aceito em:
21/07/2023
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