Transcranial direct current stimulation in prophylaxis of chronic migraine: systematic review
Estimulação transcraniana por corrente contínua na profilaxia da migrânea crônica: revisão sistemática
Helena Renata Silva Cysneiros; Kelly Sukar Cavalcanti de Oliveira; Artur Henrique Galvão Bruno da Cunha; Katia Karina do Monte-Silva; Daniella Araújo de Oliveira; Marcelo Moraes Valença
Abstract
BACKGROUND AND OBJECTIVES: To examine the latest research on transcranial direct current stimulation (tDCS), including protocols and outcomes in patients with chronic migraine who have received prophylactic treatment.
CONTENTS: This is a systematic review (PROSPERO - CRD42023454740), covering research in the last 5 years. Studies with simultaneous interventions, reviews, pilots, and special cases were excluded, aiming for a homogeneous sample of patients with chronic migraine. Of the initial 64 articles, 5 met the criteria. tDCS in the primary motor and ventral prefrontal cortex showed positive results, with improvements in quality of life and reduction in frequency and intensity of the episodes, as well as benefits for anxiety and depression. Anodal stimulation in the left primary motor cortex and left ventral lateral prefrontal cortex and cathodal stimulation in the left motor and sensory cortex showed better results.
CONCLUSION: tDCS has potential as a prophylactic intervention for chronic migraine, standing out for its tolerability and positive results. More research, with similar protocols are recommended for a more robust analysis of tDCS as an effective therapeutic alternative.
Keywords
Resumo
JUSTIFICATIVA E OBJETIVOS: Examinar as pesquisas mais recentes sobre estimulação transcraniana por corrente contínua (ETCC), incluindo protocolos e resultados em pacientes com migrânea crônica que receberam tratamento profilático.
CONTEÚDO: Uma revisão sistemática (PROSPERO - CRD42023454740), abrangendo pesquisas realizadas nos últimos 5 anos. Foram excluídos estudos com intervenções simultâneas, revisões, pilotos e casos especiais, visando uma amostra homogênea de pacientes com migrânea crônica. Dos 64 artigos iniciais, 5 preencheram os critérios. A ETCC no córtex motor primário e pré-frontal ventral apresentou resultados positivos, com melhora na qualidade de vida e redução na frequência e intensidade dos episódios, além de benefícios para ansiedade e depressão. A estimulação anódica no córtex motor primário esquerdo e no córtex pré-frontal lateral ventral esquerdo e a estimulação catódica no córtex motor e sensorial esquerdo apresentaram melhores resultados.
CONCLUSÃO: A ETCC tem potencial como intervenção profilática para migrânea crônica, destacando-se por sua tolerabilidade e resultados positivos. Recomenda-se a realização de mais pesquisas, com protocolos semelhantes, para uma análise mais robusta da ETCC como alternativa terapêutica eficaz.
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References
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Submitted date:
02/08/2024
Accepted date:
05/06/2024
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