Brazilian Journal of Pain
https://brjp.org.br/article/doi/10.5935/2595-0118.20250006-en
Brazilian Journal of Pain
Review Article

Safety of palliative cancer patients using morphine for pain control: scoping review

Segurança do paciente oncológico paliativo em uso de morfina para o controle da dor: revisão de escopo

Janillê Luciana Araújo; Erica Brandão de Moraes; Barbara Pompeu Chistovam; Aline Lima Pestana Magalhães

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Abstract

BACKGROUND AND OBJECTIVES: The objective of this study was to map the safety practices of morphine use for pain control in palliative cancer patients.

CONTENTS: This is a scoping review that followed the methodology of the Joanna Briggs Institute (JBI) to answer the question: what is the evidence on safety practices for the use of morphine for pain control in palliative cancer patients? The search was carried out in the Medline, LILACS, Scopus, Embase, Web of Science, Cochrane and CINAHL databases, as well as in the gray literature. The titles and abstracts were evaluated by two independent reviewers, and the selected papers were read in full. The data extracted is presented in the form of tables accompanied by a narrative summary. The 21 articles selected identified 14 service management practices in the use of morphine, 24 safety practices related to the prescription of morphine, 15 safety practices related to the preparation and administration of morphine and characterized 16 risks and 8 adverse reactions.

CONCLUSION: Through the identified practices, professionals can plan safe care, managing risks, adverse reactions, and promoting better control of cancer pain.

Keywords

Adverse effects; Drug-related adverse reactions; Morphine; Pain management; Patient safety

Resumo

JUSTIFICATIVA E OBJETIVOS: O objetivo deste estudo foi mapear as práticas de segurança do uso de morfina para o controle da dor em pacientes oncológicos paliativos.

CONTEÚDO: Trata-se de uma revisão de escopo que seguiu a metodologia do Instituto Joanna Briggs (JBI) para responder à pergunta: quais as evidências sobre as práticas de segurança do uso de morfina para o controle da dor em pacientes oncológicos paliativos? A busca foi realizada nas bases de dados Medline, LILACS, Scopus, Embase, Web of Science, Cochrane e CINAHL, bem como na literatura cinzenta. Os títulos e resumos foram avaliados por dois revisores independentes, e os trabalhos selecionados foram lidos na íntegra. Os dados extraídos estão apresentados em forma de tabelas acompanhadas de resumo narrativo. Dos 21 artigos selecionados, foram identificadas 14 práticas de gestão dos serviços no uso da morfina, 24 práticas de segurança relacionadas à prescrição de morfina, 15 práticas de segurança relacionadas ao preparo e administração de morfina, e caracterizados 16 riscos e 8 reações adversas.

CONCLUSÃO: Por meio das práticas identificadas, os profissionais podem planejar um cuidado seguro, gerenciando riscos, reações adversas e promovendo um melhor controle da dor oncológica.

Palavras-chave

Efeitos adversos; Manejo da dor; Morfina; Reações adversas relacionadas a fármacos; Segurança do paciente

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Submitted date:
07/05/2024

Accepted date:
10/02/2024

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